Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.3
USERS' SCORE
Good
Based on 27 Reviews
8.2
Supplement Facts
Serving Size: 5 Tablets
Amount Per Serving
%DV
Vitamin D3 (as cholecalciferol)
10 mcg (400 IU)
50%
Calcium (as calcium citrate)
1,000 mg
77%
Magnesium (as magnesium oxide, magnesium citrate)
500 mg
119%
Sodium
20 mg
<1%
Top Medical Research Studies
7
We investigated how choline magnesium trisalicylate (CMT) helps alleviate bone pain in patients with metastatic cancer. In a carefully designed study involving 26 participants, we compared CMT against a placebo in a crossover format, measuring pain relief at multiple intervals after dosing.
While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
Read More
7
We evaluated the effects of pamidronate therapy on children with osteogenesis imperfecta type III. Over the course of treatment, we saw reductions in bone pain, alongside a significant decrease in fracture incidence.
The therapy positively impacted children's daily activities and their overall mobility. Importantly, the treatment was found to be safe, although some patients experienced mild side effects like low calcium levels and a fever. Overall, our findings suggest that bisphosphonate therapy is beneficial for management in these young patients.
The therapy positively impacted children's daily activities and their overall mobility. Importantly, the treatment was found to be safe, although some patients experienced mild side effects like low calcium levels and a fever. Overall, our findings suggest that bisphosphonate therapy is beneficial for management in these young patients.
Read More
8
We explored the impact of calcium treatment on bone pain in patients who developed osteomalacia, a condition linked to intravenous iron infusions. Our focus was on a group of 13 patients diagnosed with this condition, who experienced low phosphate levels due to excess fibroblast growth factor 23 (iFGF23) after receiving ferric carboxymaltose (FCM) infusions.
After halting the FCM infusions, these patients were given supportive treatment, which included phosphate, calcium, and active Vitamin D supplementation. We observed improvements in biochemical markers, including increased phosphate levels and reduced pain scores. However, it’s important to note that while calcium was part of the treatment regimen, we could not isolate its specific effects on bone pain from the other supportive measures used.
Ultimately, our findings highlight the importance of monitoring phosphate levels in patients receiving FCM, and stopping these infusions effectively addresses phosphate wasting. Although supportive treatment showed improvements in pain and bone density, the direct impact of calcium on bone pain remains unclear given the combination of treatments involved.
After halting the FCM infusions, these patients were given supportive treatment, which included phosphate, calcium, and active Vitamin D supplementation. We observed improvements in biochemical markers, including increased phosphate levels and reduced pain scores. However, it’s important to note that while calcium was part of the treatment regimen, we could not isolate its specific effects on bone pain from the other supportive measures used.
Ultimately, our findings highlight the importance of monitoring phosphate levels in patients receiving FCM, and stopping these infusions effectively addresses phosphate wasting. Although supportive treatment showed improvements in pain and bone density, the direct impact of calcium on bone pain remains unclear given the combination of treatments involved.
Read More
Most Useful Reviews
9
Increased bone density
175 people found this helpful
I find this product excellent! It delivered the expected results; my skin, hair, and nails look better, and both my mother (59) and grandmother (91) have significantly improved their bone density, according to their densitometry results. The daily dose requires 5 capsules, which is convenient as the body can't process over 500 mg of calcium at once. The balance of components is optimal - calcium is twice that of magnesium, with added vitamin D3. All ingredients are in a digestible form and the product avoids causing constipation, unlike other calcium options. It's also cost-effective here compared to Russian pharmacies.
Read More
9
Pain relief during pregnancy
25 people found this helpful
These American vitamins were my first trial. During pregnancy, I suffered from symphysitis, with severe bone pain. My doctor recommended calcium, but initial attempts with other brands failed to help. However, after trying Solgar, the pain diminished dramatically within days, allowing me to move freely again. I attribute my recovery to this effective calcium supplement. I continue to take it regularly alongside magnesium to alleviate occasional leg cramps.
Read More
9
Eliminated bone pain
5 people found this helpful
I feel fantastic after taking this; my bone pain has ceased, and my joints no longer hurt. I plan to check my vitamin D3 levels in my blood after the course, as I had a deficiency prior to starting the medication.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.3
- All Researches
8
We explored the impact of calcium treatment on bone pain in patients who developed osteomalacia, a condition linked to intravenous iron infusions. Our focus was on a group of 13 patients diagnosed with this condition, who experienced low phosphate levels due to excess fibroblast growth factor 23 (iFGF23) after receiving ferric carboxymaltose (FCM) infusions.
After halting the FCM infusions, these patients were given supportive treatment, which included phosphate, calcium, and active Vitamin D supplementation. We observed improvements in biochemical markers, including increased phosphate levels and reduced pain scores. However, it’s important to note that while calcium was part of the treatment regimen, we could not isolate its specific effects on bone pain from the other supportive measures used.
Ultimately, our findings highlight the importance of monitoring phosphate levels in patients receiving FCM, and stopping these infusions effectively addresses phosphate wasting. Although supportive treatment showed improvements in pain and bone density, the direct impact of calcium on bone pain remains unclear given the combination of treatments involved.
After halting the FCM infusions, these patients were given supportive treatment, which included phosphate, calcium, and active Vitamin D supplementation. We observed improvements in biochemical markers, including increased phosphate levels and reduced pain scores. However, it’s important to note that while calcium was part of the treatment regimen, we could not isolate its specific effects on bone pain from the other supportive measures used.
Ultimately, our findings highlight the importance of monitoring phosphate levels in patients receiving FCM, and stopping these infusions effectively addresses phosphate wasting. Although supportive treatment showed improvements in pain and bone density, the direct impact of calcium on bone pain remains unclear given the combination of treatments involved.
Read More
7
Promising drug delivery for osteoporosis
We developed a novel drug delivery system combining denosumab and magnesium within metal-organic frameworks to target osteoarthritis. The framework showed good potential for loaded drug release, delivering about 72% of denosumab in just 8 hours.
Additionally, it released magnesium ions, which are beneficial for bone formation. Our cytotoxicity tests demonstrated that the system is biocompatible and encourages cell growth over time. While our findings are promising for pain relief linked to osteoporosis, further studies are needed to confirm effectiveness in real-world scenarios.
Additionally, it released magnesium ions, which are beneficial for bone formation. Our cytotoxicity tests demonstrated that the system is biocompatible and encourages cell growth over time. While our findings are promising for pain relief linked to osteoporosis, further studies are needed to confirm effectiveness in real-world scenarios.
Read More
7
We evaluated the effects of pamidronate therapy on children with osteogenesis imperfecta type III. Over the course of treatment, we saw reductions in bone pain, alongside a significant decrease in fracture incidence.
The therapy positively impacted children's daily activities and their overall mobility. Importantly, the treatment was found to be safe, although some patients experienced mild side effects like low calcium levels and a fever. Overall, our findings suggest that bisphosphonate therapy is beneficial for management in these young patients.
The therapy positively impacted children's daily activities and their overall mobility. Importantly, the treatment was found to be safe, although some patients experienced mild side effects like low calcium levels and a fever. Overall, our findings suggest that bisphosphonate therapy is beneficial for management in these young patients.
Read More
7
We investigated how choline magnesium trisalicylate (CMT) helps alleviate bone pain in patients with metastatic cancer. In a carefully designed study involving 26 participants, we compared CMT against a placebo in a crossover format, measuring pain relief at multiple intervals after dosing.
While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
Read More
User Reviews
USERS' SCORE
Good
Based on 27 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
9
Increased bone density
175 people found this helpful
I find this product excellent! It delivered the expected results; my skin, hair, and nails look better, and both my mother (59) and grandmother (91) have significantly improved their bone density, according to their densitometry results. The daily dose requires 5 capsules, which is convenient as the body can't process over 500 mg of calcium at once. The balance of components is optimal - calcium is twice that of magnesium, with added vitamin D3. All ingredients are in a digestible form and the product avoids causing constipation, unlike other calcium options. It's also cost-effective here compared to Russian pharmacies.
Read More
9
Pain relief during pregnancy
25 people found this helpful
These American vitamins were my first trial. During pregnancy, I suffered from symphysitis, with severe bone pain. My doctor recommended calcium, but initial attempts with other brands failed to help. However, after trying Solgar, the pain diminished dramatically within days, allowing me to move freely again. I attribute my recovery to this effective calcium supplement. I continue to take it regularly alongside magnesium to alleviate occasional leg cramps.
Read More
9
Eliminated bone pain
5 people found this helpful
I feel fantastic after taking this; my bone pain has ceased, and my joints no longer hurt. I plan to check my vitamin D3 levels in my blood after the course, as I had a deficiency prior to starting the medication.
Read More
7.5
Reduced heaviness
4 people found this helpful
I purchased this for my father on a doctor's recommendation following his leg operation and bone issues. Since he began these tablets, he no longer feels heaviness in his leg—a relief that domestic tablets failed to provide. This manufacturer can be relied upon.
Read More
9
Muscle pain relief
1 people found this helpful
People who are often tense, have long-lasting muscle pain, or have weak bones should consider taking this. I suspect I might have a magnesium deficiency, as I usually experience muscle pain even with minimal exercise, which can last for 2 weeks. If I face musculoskeletal inflammation or injuries, my recovery takes longer. I take only 2 tablets daily, well below the recommended amount, and they've worked wonders. The muscle pain that lingered was gone the next day. While I increased to 3 tablets once and felt soreness, reverting to 2 restored my health. Importantly, my insomnia vanished; I no longer wake up multiple times at night. I recommend magnesium for anyone struggling with insomnia or heightened body tension.
Read More
Frequently Asked Questions
9
Pain relief during pregnancy
25 people found this helpful
These American vitamins were my first trial. During pregnancy, I suffered from symphysitis, with severe bone pain. My doctor recommended calcium, but initial attempts with other brands failed to help. However, after trying Solgar, the pain diminished dramatically within days, allowing me to move freely again. I attribute my recovery to this effective calcium supplement. I continue to take it regularly alongside magnesium to alleviate occasional leg cramps.
9
Eliminated bone pain
5 people found this helpful
I feel fantastic after taking this; my bone pain has ceased, and my joints no longer hurt. I plan to check my vitamin D3 levels in my blood after the course, as I had a deficiency prior to starting the medication.
9
Promotes bone health
1 people found this helpful
This product is vital for maintaining the health of my bones and teeth. After a few weeks of use, I've noticed positive changes in my well-being. The combination of calcium, magnesium, and vitamin D enhances bone and teeth health. Its easy absorption impressed me, and I recommend it to anyone looking for high-quality support for their bone and tooth health.
6
Cramps disappeared
1 people found this helpful
I took this Solgar calcium tablet three times daily for three months. It's particularly advisable for those over 50. Although I did not do a densitometry test, I took it prophylactically. I noticed that the cramps in my calf muscles disappeared, and my son benefited from this calcium after a forearm fracture, showing good healing after three months of use. We recommend this supplement based on our experience and are reordering.
9
Increased bone density
175 people found this helpful
I find this product excellent! It delivered the expected results; my skin, hair, and nails look better, and both my mother (59) and grandmother (91) have significantly improved their bone density, according to their densitometry results. The daily dose requires 5 capsules, which is convenient as the body can't process over 500 mg of calcium at once. The balance of components is optimal - calcium is twice that of magnesium, with added vitamin D3. All ingredients are in a digestible form and the product avoids causing constipation, unlike other calcium options. It's also cost-effective here compared to Russian pharmacies.
9
Muscle pain relief
1 people found this helpful
People who are often tense, have long-lasting muscle pain, or have weak bones should consider taking this. I suspect I might have a magnesium deficiency, as I usually experience muscle pain even with minimal exercise, which can last for 2 weeks. If I face musculoskeletal inflammation or injuries, my recovery takes longer. I take only 2 tablets daily, well below the recommended amount, and they've worked wonders. The muscle pain that lingered was gone the next day. While I increased to 3 tablets once and felt soreness, reverting to 2 restored my health. Importantly, my insomnia vanished; I no longer wake up multiple times at night. I recommend magnesium for anyone struggling with insomnia or heightened body tension.
7.5
Improved sleep quality
2 people found this helpful
Goodbye apathy and sleepless nights! My husband and I are finishing our first jar of these vitamins and have noted significant improvements in wellbeing – no fatigue and we are not feeling apathetic, especially during autumn. Before ordering, we tested our D3 levels, which were low. I’ve begun sleeping better, possibly due to magnesium. I'm pleased to know my bones are receiving nourishment. I recommend these vitamins after appropriate tests.
7.5
Healthy bone support
2 people found this helpful
This complex truly delivers results. Magnesium aids in calcium transport and stimulates calcitonin, promoting calcium influx into the bone. It also contains Vitamin D (400 IU), necessary for calcium absorption, benefiting bone, joint, and dental health. Although the package includes a substantial number of 300 tablets, it's reassuring to have a good supply.
6
Maintaining bone density
I take this for my bone health alongside other calcium supplements. It seems to be preventing a decrease in bone density. I will continue using it.
9
Strong bone support
8 people found this helpful
The perfect combination of Ca, Mg, and D3! A super-hit from Solgar! I take them for general support of my bone system. This 3-in-1 combination is very effective! I felt the benefits from the first weeks—stronger teeth and nails, thicker hair, and improved skin! The recommended intake is 5 tablets daily, but I find this too much and take just 1-2 daily, achieving great results! I’ll give it 5 stars and will reorder. If you find my feedback helpful, feel free to benefit from my discount.
9
Improved bone density
1 people found this helpful
After being diagnosed with BMD of -2.4, I've taken this calcium supplement for over three years. When re-examined, my score improved by 0.3. I manage my diet to ensure calcium absorption while exercising. I highly recommend this for those concerned about bone density! Do note the large pill size before purchasing.
7
We investigated how choline magnesium trisalicylate (CMT) helps alleviate bone pain in patients with metastatic cancer. In a carefully designed study involving 26 participants, we compared CMT against a placebo in a crossover format, measuring pain relief at multiple intervals after dosing.
While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
8
We explored the impact of calcium treatment on bone pain in patients who developed osteomalacia, a condition linked to intravenous iron infusions. Our focus was on a group of 13 patients diagnosed with this condition, who experienced low phosphate levels due to excess fibroblast growth factor 23 (iFGF23) after receiving ferric carboxymaltose (FCM) infusions.
After halting the FCM infusions, these patients were given supportive treatment, which included phosphate, calcium, and active Vitamin D supplementation. We observed improvements in biochemical markers, including increased phosphate levels and reduced pain scores. However, it’s important to note that while calcium was part of the treatment regimen, we could not isolate its specific effects on bone pain from the other supportive measures used.
Ultimately, our findings highlight the importance of monitoring phosphate levels in patients receiving FCM, and stopping these infusions effectively addresses phosphate wasting. Although supportive treatment showed improvements in pain and bone density, the direct impact of calcium on bone pain remains unclear given the combination of treatments involved.
After halting the FCM infusions, these patients were given supportive treatment, which included phosphate, calcium, and active Vitamin D supplementation. We observed improvements in biochemical markers, including increased phosphate levels and reduced pain scores. However, it’s important to note that while calcium was part of the treatment regimen, we could not isolate its specific effects on bone pain from the other supportive measures used.
Ultimately, our findings highlight the importance of monitoring phosphate levels in patients receiving FCM, and stopping these infusions effectively addresses phosphate wasting. Although supportive treatment showed improvements in pain and bone density, the direct impact of calcium on bone pain remains unclear given the combination of treatments involved.
References
- von Brackel FN, Grambeck J, Barvencik F, Amling M, Oheim R. In-depth clinical characterization of intravenous iron infusion-induced hypophosphatemic osteomalacia and its resolution. JBMR Plus. 2024;8:ziae139. 10.1093/jbmrpl/ziae139
- Alsaikhan F, Mahmoud MZ, Suliman M. Synthesis and characterization of novel denosumab/magnesium-based metal organic frameworks nanocomposite prepared by ultrasonic route as drug delivery system for the treatment of osteoporosis. Front Bioeng Biotechnol. 2023;11:1153969. 10.3389/fbioe.2023.1153969
- Jakubowska-Pietkiewicz E, Chlebna-Sokół D. New trends in the treatment of osteogenesis imperfecta type III - own experience. Ortop Traumatol Rehabil. 2008;10:593.
- Johnson JR, Miller AJ. The efficacy of choline magnesium trisalicylate (CMT) in the management of metastatic bone pain: a pilot study. Palliat Med. 1994;8:129.
